Seroepidemiology in Chlamydia pneumoniae — atherosclerosis association

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Seroepidemiology in Chlamydia pneumoniae-- atherosclerosis association.

[1] van Hout BA, Simoons ML. Cost-effectiveness of HMG coenzyme reductase inhibitors. Whom to treat? Eur Heart J 2001; 22: 751–61. [2] Houterman S, Boshuizen HC, Verschuren VMM et al. Predicting cardiovascular risk in the elderly in different European countries. Eur Heart J 2002; 23: 294–300, doi:10.1053/euhj.2001.2898. [3] Clarke R, Lewington S, Youngman L, Sherliker P, Peto R, Collins R. Unde...

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Chlamydia pneumoniae and atherosclerosis.

OBJECTIVE To review the literature for evidence that chronic infection with Chlamydia pneumoniae is associated with atherosclerosis and acute coronary syndromes. DATA SOURCES MEDLINE and Institute of Science and Information bibliographic databases were searched at the end of September 1998. Indexing terms used were chlamydi*, heart, coronary, and atherosclerosis. Serological and pathological ...

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Atherosclerosis and Chlamydophila (chlamydia) Pneumoniae

The concept that atherosclerosis was induced by environmental factors such as smoking and high fat intake was perturbated when inflammation was found to be prominent in atherosclerotic lesions. Chlamydophila pneumoniae but also other microbes inducing chronic endothelial infections have been implicated, particularly cytomegalovirus (CMV) and the gastric pathogen Helicobacter pylori. Large sero-...

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Role of Chlamydia pneumoniae in atherosclerosis.

Cardiovascular disease, resulting from atherosclerosis, is a leading cause of global morbidity and mortality. Genetic predisposition and classical environmental risk factors explain much of the attributable risk for cardiovascular events in populations, but other risk factors for the development and progression of atherosclerosis, which can be identified and modified, may be important therapeut...

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Molecular detection and seroepidemiology of the Chlamydia pneumoniae bacteriophage (PhiCpn1).

Recent whole-genome analysis has demonstrated limited genetic variation in Chlamydia pneumoniae, with one strain (AR39) containing a 4,524 nucleotide single-stranded DNA bacteriophage, PhiCpn1. Using PCR, reverse transcription (RT)-PCR, and Western blotting, we confirmed the presence and functional expression of PhiCpn1 in C. pneumoniae strain AR39 and its absence in strain CWL029. Six addition...

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ژورنال

عنوان ژورنال: European Heart Journal

سال: 2002

ISSN: 0195-668X

DOI: 10.1053/euhj.2001.2913